Este fenómeno es conocido como efecto Jod-Basedow. El tratamiento con propiltiouracilo en dosis decrecientes consiguió un estado eutiroideo y mejoró la . Efectos de las hormomas tiroideas en el corazón. Visits . por el efecto de Wolff- Chaikoff, además de hipertiroidismo (mediado por el efecto de Jod-Basedow. de hipertiroidismo (mediado por el efecto de Jod-Basedow. En ambos casos, la causa subyacente es por la alta concentración de yodo en este medicamento.

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The Jod-Basedow phenomenon is differentiated from Basedow’s diseasewhich is occasionally used as a synonym for Graves disease. Universidad Tecnolica de Pereira, Risaralda.

Wolff–Chaikoff effect – Wikipedia

Overall, hyperthyroidism is characterized by an increase in resting heart rate, blood volume, stroke volume, myocardial contractility, and ejection fraction. Continuing navigation will be considered as ffecto of this use. Med Clin North Am ;96 2: Blood sugar regulation Calcium metabolism. Thyroiditis and iodide mumps following an angioplasty. The Wolff—Chaikoff effect[1] discovered by Drs. On the other hand, when thyrocites have low iodine levels and are exposed to a high iodine concentration, they increase significantly their production of thyroid hormone thus leading to hyperthyroidism, a phenomenon known as Jod-Basedow effect.

Iodide induced hyperthyroidism with computed tomography contrast fluids.

However, unlike the Wolff-Chaikoff effectthe Jod-Basedow effect does not occur in persons with normal thyroid glands, as thyroid hormone synthesis and release in normal persons is controlled by pituitary TSH secretion which does not allow hyperthyroidism when extra iodine is ingested. Longo, Joseph Loscalzo Clicamente, te puede llevar a hipotiroidismo.


From Monday to Friday from 9 a. Cardiac and hemodynamic consequences of hyperthyroidism. Both hypothyroidism and hyperthyroidism increase the risk of coronary artery disease, left cardiomyopathy, electrophysiological abnormalities, and all-cause mortality.

Jod-Basedow phenomenon – Wikipedia

Views Read Edit View jkd. Fortschr Geb Rontgenstrahlen Nuklearmed Ergan- zugsbd ; Acta radiol ;54 1: The Wolff—Chaikoff effect is known as an autoregulatory phenomenon that inhibits organification in the thyroid glandthe formation of thyroid hormones inside the thyroid follicle, and the release of thyroid hormones into the bloodstream.

La exposici a cantidades excesivas de yodo bloquea la actividad de la enzima peroxidasa tiroidea TPOun feneno conocido como efecto de Wolff-Chaikoff. The Jod-Basedow effect does not occur in persons with normal thyroid glands who ingest extra iodine in any form.

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Thyroid functions after contrast agent administration for coronary angiography: Thyroid hormones upregulate the expression of the sarcoplasmic reticulum calcium-activated ATPase and downregulate the expression of phospholamban.

Effect on thyroid function. People who have Graves diseasetoxic efectk goiteror various types of thyroid adenoma are also at risk of Jod-Basedow effect when they ingest extra iodine.

Cardiovascular and hemodynamic changes in a hypothyroid state. Physiology of the endocrine system. CiteScore measures average citations received per document published. Subclinical thyroid dysfunctions are independent risk factors for mortality in a 7.

Jod-Basedow phenomenon

The Wolff—Chaikoff effect is an effective means of rejecting a large quantity of imbibed iodide, and therefore preventing the thyroid from synthesizing large quantities of thyroid hormone. In general, subclinical hypothyroidism increases the risk of coronary heart disease CHD mortality and CHD events, but not of total mortality.


In both instances, the underlying cause is the high concentration of iodine in this medication. Association between iodinated contrast media exposure and incident hyperthyroidism and hypothyroidism.

Por el contrario, cuando un tirocito contiene valores bajos de yodo y es expuesto a elevadas concentraciones del mismo, aumenta de forma significativa la producci de hasedow tiroidea, llevando frecuentemente a hipertiroidismo clico y bioquico, feneno conocido como efecto de Jod-Basedow. This page was last edited on 7 Augustat The effect is rapid because of rapid inhibition of intrathyroid organification of iodide acute Wolff—Chaikoff effect efefto saturation of the iodide-transport mechanism.

Animal experimental and clinical studies.

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This page was last edited on 10 Augustat By using this site, you agree to the Terms of Use and Privacy Policy. Hypothalamic—pituitary—thyroid axis Hypothalamic—pituitary—adrenal baseeow Hypothalamic—pituitary—gonadal axis Hypothalamic—pituitary—somatotropic axis Hypothalamic—pituitary—prolactin axis Hypothalamic—neurohypophyseal system Renin—angiotensin system.

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