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New Haven, Connecticut - Wikipedia

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His factory, along with that of Simeon Northand the lively clock-making and brass hardware sectors, contributed to making early Connecticut a powerful manufacturing economy; so many arms manufacturers sprang up that the state became known as "The Arsenal of America". It was in Whitney's gun-manufacturing plant that Samuel Colt invented the automatic revolver in Many other talented machinists and firearms designers would go on to found successful firearms manufacturing companies in New Haven, including Oliver Winchester and O.

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The Farmington Canalcreated in the early 19th century, was a short-lived transporter of goods into the interior regions of Connecticut and Massachusetts, and ran from New Haven to Northampton, Massachusetts.

Site of the Winchester Repeating Arms Companywhich has since been converted to Science Park at Yale, a complex for start-ups and technological firms New Haven was home to one of the important early events in the burgeoning anti-slavery movement when, inthe trial of mutineering Mende tribesmen being transported as slaves on the Spanish slaveship Amistad was held in New Haven's United States District Court. See "Museums" below for more information.

Abraham Lincoln delivered a speech on slavery in New Haven in[16] shortly before he secured the Republican nomination for President. The American Civil War boosted the local economy with wartime purchases of industrial goods, including that of the New Haven Arms Companywhich would later become the Winchester Repeating Arms Company. Winchester would continue to produce arms in New Haven untiland many of the buildings that were a part of the Winchester plant are now a part of the Winchester Repeating Arms Company Historic District.

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Jewish immigration to New Haven has left an enduring mark on the city. Westville was the center of Jewish life in New Haven, though today many have fanned out to suburban communities such as Woodbridge and Cheshire.

Post-industrial era and urban redevelopment[ edit ] The historic New Haven Greenca. The city reached its peak population after World War II. Moreover, as in other U. One author suggested that aggressive redlining and rezoning made it difficult for residents to obtain financing for older, deteriorating urban housing stock, thereby condemning such structures to deterioration.

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Lee began some of the earliest major urban renewal projects in the United States. Certain sections of downtown New Haven were redeveloped to include museums, new office towers, a hotel, and large shopping complexes.

This is especially true for OTC medications that contain caffeine. If you find that you need to use acute migraine treatment frequently, talk to your health care provider about preventive medications.

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Preventive strategies for migraine include both drug treatment and behavioral therapy or lifestyle adjustments. People should consider using preventive migraine drugs if they have: Migraines that are not helped by acute treatment drugs Frequent attacks more than once per week Side effects from acute treatment drugs or contraindications to taking them The main preventive drug treatments for migraine are: Beta-blocker drugs [often propranolol Inderal, generic or timolol Blocadren ] Anti-seizure drugs [often divalproex Depakote, genericvalproate Depacon, generic or topiramate Topamax, generic ] Tricyclic antidepressants [often amitriptyline Elavil, generic ] or the dual inhibitor antidepressant venlafaxine Effexor, generic The triptan frovatriptan Frova for menstruation-associated migraine OnabotulinumtoxinA Botox injection is approved for prevention of migraine, but it appears to work best for chronic not episodic migraine.

Certain herbal and dietary supplements, such as butterbur Petasites hybridus and riboflavin, may be effective for migraine prevention. A preventive medication strategy needs to be carefully and individually tailored, taking into account a person's medical history and coexisting medical conditions. Migraine drugs can have serious side effects.

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Preventive medicine is often started at a low dose, and then gradually increased. It may take 2 to 3 months for a drug to achieve its full effect. Preventive treatment may be needed for 6 to 12 months or longer. Most people take preventive medications on a daily basis, but some people use these drugs intermittently for example, for preventing menstrual migraine.

Some medications, especially certain oral contraceptives, may increase frequency of migraine in some women. In such cases, changing the type of contraceptive or stopping it results in improved migraine control. You can also help prevent migraines by identifying and avoiding potential triggers, such as specific foods. Relaxation therapy and stress reduction techniques may also help.

See Lifestyle section in this report. Migraine Treatment for Children Most children with migraines need only mild pain relievers and home remedies such as ginger tea to treat their headaches. The American Academy of Neurology's practice guidelines for children and adolescents recommend the following drug treatments: For children age 6 and older, ibuprofen Advil, generic is recommended. Acetaminophen Tylenol, generic may also be effective.

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Acetaminophen works faster than ibuprofen, but the effects of ibuprofen last longer. For adolescents age 12 and older, sumatriptan Imitrex nasal spray is recommended. Migraine Prevention for Children Non-drug methods, including biofeedback and muscle relaxation techniques, may be helpful. If these methods fail, preventive medications may be used, although evidence is weak on the effectiveness of standard migraine prevention drugs in children.

If medication overuse causes rebound migraines to develop, you will need to stop taking the drug. If caffeine is the trigger, you may only need to reduce coffee or tea intake.

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People often have the option of stopping abruptly or gradually: Most headache drugs can be stopped abruptly, but talk to your provider first. Certain non-headache medications, such as anti-anxiety drugs, anti-seizure drugs, or beta-blockers, require gradual withdrawal under medical supervision. Your provider may recommend you take other pain medicines during the first days.

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Examples of drugs that may be used include dihydroergotamine, NSAIDs in mild casescorticosteroids, or valproate. Expect headaches to get worse after you stop taking medication, no matter which method you use.

Most people feel better within 2 weeks, although headache symptoms can persist up to 16 weeks and in rare cases even longer. Medications and Devices for Treating Migraine Attacks Many different medications are used to treat migraines.

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Some migraines respond to non-prescription pain relievers such as ibuprofen, acetaminophen, naproxen, or aspirin. Among prescription drugs, triptans and ergotamine are the only types of medications approved by the U.

Other types of drugs, including opioids and barbiturates, are sometimes prescribed off-label for migraine treatment but they can have dangerous side effects.

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Opioids and barbiturates are not approved by the FDA for migraine relief. Over-the-counter OTC painkillers, also called analgesics, are available without a prescription.